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Colangiocarcinoma y hepatocolangiocarcinoma combinado en pacientes con cirrosis
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Salinas, Marcelo

; Simian, Daniela

; Carreño, Laura

; Cattaneo, Máximo

; Urzúa, Álvaro

; Sauré, Alex

; Lembach, Hanns

; Castillo, Jaime

; Díaz, Juan C.

; Poniachik, Jaime

Revista médica de Chile

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Nov 2022, Volume 150 Nº 11 Páginas 1431 - 1437

Resumo: Es En | Texto: Es En | PDF: Es | PDF: En

Background: Cholangiocarcinoma (CCA) is a primary hepatic tumor, frequently found in patients with liver cirrhosis and biliary tract diseases. Its varieties include isolated CCA or “combined hepatocellular-cholangiocarcinoma” (cHCC-CCA). The latter is uncommon, with poorly defined diagnostic criteria and natural history. Aim: To characterize patients with cirrhosis with a pathological diagnosis of CCA and cHCC-CCA. Material and Methods: Forty-nine liver biopsies with a pathological diagnosis of CCA were reviewed. The clinical records of patients were reviewed to fetch demographic variables, etiology of cirrhosis and clinical presentation. Results: Eight of the 49 patients had cirrhosis (16% of CCA biopsies reviewed). Their median age was 64 (27-71) years and five were females. Four patients had CCA, three patients cHCC-CCA and one had a bifocal tumor. Patients in the CCA group were more commonly symptomatic. Alpha-fetoprotein and CA 19-9 levels were elevated in one of eight and four of six patients, respectively. Within 12 months from diagnosis, five of eight patients died. Conclusions: In most of these cases, the diagnosis of cHCC-CCA and CCA was made in the liver explant study without previous imaging diagnosis. This reinforces the usefulness of the histological study, in specific cases, prior to liver transplantation and emphasizes the importance of systematic explant exploration in these cases.

Consenso chileno de diagnóstico y manejo de neoplasias quísticas pancreáticas. Club de páncreas Chile-SCHGE
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Espino, Alberto

; Vargas, José Ignacio

; Mancilla, Carla

; Muñoz, Pablo

; Martínez, Waldo

; Menéndez, Alejandra

; Jara, Daniela

; Mansilla, Rodrigo

; Schiappacasse, Giancarlo

; Santamarina, Mario

; Huete, Álvaro

; Candia, Roberto

; Silva, Felipe

; Castillo, Cecilia

; Richter, Hugo

; Mejía, Ricardo

; Vial, Paula

; Robles, Ignacio

; Martínez, Jorge

; Jarufe, Nicolás

; Briceño, Eduardo

; Lembach, Hanns

; Zoroquiain, Pablo

; Roa, Juan Carlos

; Walker, Kenneth

; Torres, Javiera

; Carreño, Laura

; Castiblanco, Adriana

; Fernández, Wanda

; Ríos, Álvaro

; Chandia, Javiera

; Ayala, María José

; Rojas, Tamara

; Verdugo, Jorge

; Berger, Zoltán

Revista médica de Chile

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Dez 2021, Volume 149 Nº 12 Páginas 1773 - 1786

Resumo: En Es | Texto: En Es | PDF: En | PDF: Es

Pancreatic cystic neoplasms (PCN) are frequently detected on abdominal images performed for non-pancreatic indications. Their prevalence in asymptomatic population ranges from 2.7 to 24.8%, and increases with age. There are several types of pancreatic cysts. Some may contain cancer or have malignant potential, such as mucinous cystic neoplasms, including mucinous cystadenoma (MCN) and intraductal papillary mucinous neoplasms (IPMN). In contrast, others are benign, such as serous cystadenoma (SCA). However, even those cysts with malignant potential rarely progress to cancer. Currently, the only treatment for pancreatic cysts is surgery, which is associated with high morbidity and occasional mortality. The Board of the Chilean Pancreas Club of the Chilean Gastroenterology Society developed the first Chilean multidisciplinary consensus for diagnosis, management, and surveillance of PCN. Thirty experts were invited and answered 21 statements with five possible alternatives: 1) fully agree; 2) partially agree; 3) undecided; 4) disagree and 5) strongly disagree. A consensus was adopted when at least 80% of the sum of the answers “fully agree” and “partially agree” was reached. The consensus was approved by the Board of Directors of the Chilean Pancreas Club for publication.

https://doi.org/10.4067/s0034-98872021001201773 73 downloads

Subcutaneous Sweet’s syndrome associated with the onset of Behcet’s disease,
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Vargas-Mora, Pablo

; Valenzuela, Fernando

; Kaplan, Viera

; Carreño, Laura

Anais Brasileiros de Dermatologia

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Out 2021, Volume 96 Nº 5 Páginas 644 - 645

Resumo: En | Texto: En | PDF: En

https://doi.org/10.1016/j.abd.2020.07.021 14 downloads

Tumores hepáticos primarios malignos no hepatocarcinoma ni colangiocarcinoma
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Araneda, Gonzalo

; Poniachik, Rafael

; Freundlich, Alejandro

; Carreño, Laura

; Poniachik, Jaime

Revista médica de Chile

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Jun 2019, Volume 147 Nº 6 Páginas 751 - 754

Resumo: En Es | Texto: En Es | PDF: En | PDF: Es

Background: There are several types of primary malignant hepatic tumors (PMHT) other than hepatocellular carcinoma (HCC) and cholangiocarcinoma (CC): they are infrequent and poorly known. Imaging studies could help characterize the lesions and may guide the diagnosis. However, the definitive diagnosis of PMHT is made by pathology. Aim: To review a registry of liver biopsies performed to diagnose hepatic tumors. Patients and Methods: Review of a pathology registry of liver biopsies performed for the diagnosis of liver tumors. Among these, 25 patients aged 57 ± 17 years, 60% males, in whom a liver tumor other than a HCC or CC was diagnosed, were selected for review. The medical records of these patients were reviewed to register their clinical characteristics, imaging and the pathological diagnosis performed during surgery and/ or with the percutaneous liver biopsy. Results: Ten patients (40%) had neuroendocrine tumors, six (24%) had a lymphoma and four (16%) had hepatic hemangioendothelioma. Angiosarcoma and sarcomatoid carcinoma were diagnosed in one patient each. In 22 patients (88%), neither clinical features nor imaging studies gave the correct diagnosis. Four patients (16%) had chronic liver disease. The most frequent symptoms were weight loss in 28% and abdominal pain in 24%. Conclusions: The most common PMHT other than HCC and CC were neuroendocrine tumors and lymphomas. Imaging or clinical features were not helpful to reach the correct diagnosis.

1712 downloads

El polimorfismo rs12979860 C>T en el gen Interferón lambda 4 no está asociado a riesgo de fibrosis hepática en pacientes chilenos con hepatitis crónica por virus C
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Brahm, Javier

; Urzúa, Alvaro

; Poniachik, Jaime

; Cáceres, Dante D.

; Carreño, Laura

; Venegas, Mauricio

Revista médica de Chile

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Jul 2018, Volume 146 Nº 7 Páginas 823 - 829

Resumo: En Es | Texto: En Es | PDF: En | PDF: Es

Background. Host genetic predispositions may be important determinants of liver fibrosis in patients with chronic hepatitis C (CHC). The association between Interferon-L 4 (IFNL4) rs12979860 C>T polymorphism and risk of liver fibrosis in CHC is contradictory. Aim: To evaluate the impact of IFNL4 rs12979860 polymorphism on the risk of fibrosis in patients with CHC. Material and Methods: One hundred fifty patients with CHC aged 50 ± 11 years (89 females) were genotyped for IFNL4 rs12979860 using real time PCR. Fibrosis present in liver biopsies was assessed using the METAVIR score, comparing patients with either no fibrosis, mild fibrosis, or intermediate fibrosis (F0+F1+F2, n = 96), with patients with severe fibrosis or cirrhosis (F3+F4, n = 54). Results: In F0-F2 patients the distribution of rs12979860 genotypes was 22 CC, 57 CT and 17 TT, whereas in patients F3-F4 the distribution was 10, 29 and 15, respectively. No association between IFNL4 rs12979860 genotype and risk of fibrosis was observed in uni or multivariate analyses. Conclusions: IFNL4 rs12979860 C>T polymorphism is not associated with risk of liver fibrosis in this group of patients with CHC.

https://doi.org/10.4067/s0034-98872018000700823 721 downloads

La complejidad del mercado bursátil latinoamericano a partir de un modelo autómata celular conductual
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Talero-Sarmiento, Leonardo Hernán

; Duarte-Duarte, Juan Benjamín

; Garcés-Carreño, Laura Daniela

Apuntes del Cenes

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Dez 2017, Volume 36 Nº 64 Páginas 199 - 223

Resumo: Es En Pt | Texto: Es En Pt | PDF: Es | PDF: En | PDF: Pt

Resumen La presente investigación busca evaluar el nivel de complejidad del mercado latinoamericano, mediante la construcción de un modelo autómata celular. Para ello se estudian seis índices bursátiles: COLCAP, IPSA, MERVAL, MEXBOL, SPBLPGPT e IBOV, en el periodo 2004-2016. Estas series son analizadas a partir de su comportamiento estadístico, el ajuste de retornos y la estimación de su grado de complejidad. Este último es contrastado posteriormente con el nivel de complejidad obtenido mediante la simulación de un mercado bursátil artificial, y se concluye que los mercados latinoamericanos, a pesar de presentar diferencias, suelen tener tendencias similares, ya que su grado de complejidad no puede ser pronosticado por un modelo autómata celular conductual basado netamente en la imitación.

Abstract The aim of this research is to evaluate the complexity level of Latin-American stock market using a cellular automaton model. For this purpose six indexes are studied: COLCAP, IPSA, MERVAL, MEXBOL, SPBLPGPT and IBOV respectively, during the period 2004 and 2016. The series are analyzed from their statistical behavior, adjustment of returns and estimation of its complexity. The last one is contrasted with the complexity level obtained simulating an artificial stock market model. Concluding that although Latin-American stock markets present differences they have similar tendencies and their complexity level cannot be predicted by a purely behavioral cellular automaton model.

Resumo Esta pesquisa visa avaliar o nível de complexidade do mercado da América Latina através da construção de um modelo de autômato celular; para isto e feito o estúdio de seis series de ações; COLCAP, IPSA, MERVAL , MEXBOL , SPBLPGPT e IBOV entre 2004-2016: Estas séries são analisados a partir do seu comportamento estatístico, o ajuste de retornos e estimativa da sua complexidade. Este último é então contrastado com o nível de complexidade obtida através da simulação de um mercado de ações artificial, concluindo que os mercados da América Latina, apesar de ter diferenças, muitas vezes têm tendências semelhantes e que a sua complexidade não pode ser prevista por um modelo de autômato celular puramente comportamental.

https://doi.org/10.19053/01203053.v36.n64.2017.5421 587 downloads

Reconstruction of multispectral light field (5d plenoptic function) based on compressive sensing with colored coded apertures from 2D projections
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León-López, Kareth Marcela

; Galvis-Carreño, Laura Viviana

; Arguello-Fuentes, Henry

Revista Facultad de Ingeniería Universidad de Antioquia

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Jul 2016, Nº 80 Páginas 131 - 141

Resumo: Es En | Texto: Es En | PDF: Es | PDF: En

Resumen Los sistemas de adquisición de información espacio - angular en 4D o campos de luz, han avanzado en la última década debido a la inclusión de aperturas codificadas en el camino óptico del sistema. Dichas aperturas, modulan la luz codificando la información antes de ser capturada. Tradicionalmente, estas aperturas codificadas son aperturas binarias, es decir, bloquean o dejan pasar los rayos de luz en la dimensión espacial haciendo que se capture información dispersa de la escena. En este trabajo, se reemplazan las aperturas binarias por aperturas codificadas de color, que además de modular la luz espacialmente lo hacen espectralmente. De esta forma, es posible adquirir campos de luz en múltiples longitudes de onda y aumentar su resolución espectral. La importancia de obtener información en el espectro radica en que es posible capturar características que no están presentes en el rango visible del espectro electromagnético. En este artículo, se propone un algoritmo que simula la adquisición de una imagen de campo de luz usando aperturas codificadas de color. El sistema propuesto aprovecha la redundancia de información que se presenta en la escena basándose en la teoría del muestreo compresivo, así, solo se captura una señal dispersa de la escena. La imagen multidimensional es recuperada a partir de dicha señal mediante un algoritmo de reconstrucción. Los resultados de simulación muestran la calidad de reconstrucción del campo de luz multiespectral. La calidad de las reconstrucciones obtenidas es de alrededor de 25 dB en PSNR.

Abstract In the last decade, spatio - angular (light field) acquisition systems have advanced due to the inclusion of coded apertures in the optical path. These coded apertures, modulate the light, encoding the information before being captured. Traditionally, these coded apertures are binary, i.e. block and unblock the light rays in the spatial dimension, capturing sparse information of the scene. In this work, the binary coded aperture is replaced by a colored coded aperture which modulates the source not only spatially but spectrally. Thereby, it is possible to capture light fields in multiple wavelengths yielding high spectral resolution. The spectral information provides many features of a scene in different wavelengths, these features are not present in the visible range of the electromagnetic spectrum. In this paper, an algorithm that simulates the light field sampling with colored coded apertures is proposed. The proposed algorithm, exploits the redundant information of the scene based on the compressive sensing theory thus, capturing just a sparse signal. The multidimensional image can be recovered from the underlying signal through a reconstruction algorithm. Several simulations show the quality of the multispectral light field reconstructions. The PSNR (Peak Signal to Noise Ratio) values obtained for the reconstructions are around 25 dB.

https://doi.org/10.17533/udea.redin.n80a14 686 downloads

Efecto manada en sectores económicos de las bolsas latinoamericanas: una visión pre y poscrisis subprime
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Duarte Duarte, Juan Benjamín

; Garcés Carreño, Laura Daniela

; Sierra Suárez, Katherine Julieth

Contaduría y administración

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Jun 2016, Volume 61 Nº 2 Páginas 298 - 323

Resumo: En Es | Texto: En Es | PDF: En | PDF: Es

Abstract: In recent years the behavior of the agents and what motivates them to make their investment decisions; it has been the focus of study by many researchers in the fields of economics, finance and related fields. With this in mind, this article seeks to test empirically one of these behaviors, the herd effect, using the models proposed by Christie y Huang (1995) and Chang, Cheng y Khorana (2000), in the most representative index and the sectors that compose it, of the main markets in Latin America (Brazil, Mexico, Chile, Colombia, Peru and Argentina) in the period 2002-2014, as well as in the sub periods pre and post crisis caused by the subprime mortgage. The findings of this research show that the herd effect is present in the most representative stock index in Colombia, Chile and Peru and in some of the sectors that comprise it, either in the total period and/or in sub periods pre and post crisis; in the Brazilian stock market, the effect is present in the banking sector in the total period and in the sub period of pre-crisis; Argentina stock market that effect is present in the banking sector and in the oil and gas sector, and Mexico stock market there is no evidence of this effect.

Resumen: En los últimos años, el comportamiento de los agentes y lo que los motiva a tomar sus decisiones de inversión ha sido foco de estudio de muchos investigadores en las ramas de economía, finanzas y afines. Teniendo en cuenta esto, en este artículo se busca comprobar empíricamente uno de estos comportamientos, el efecto manada, mediante los modelos propuestos por Christie y Huang (1995) y Chang, Cheng y Khorana (2000), en el índice más representativo y en los sectores que lo componen, de los principales mercados de América Latina (Brasil, México, Chile, Colombia, Perú y Argentina) para el periodo 2002-2014, así como en los subperiodos pre y poscrisis originados por las hipotecas subprime. Los hallazgos de esta investigación muestran que el efecto manada está presente en el índice más representativo del mercado bursátil de Colombia, Chile y Perú y en algunos de los sectores que lo componen, ya sea en el periodo total y/o en los subperiodos de pre y poscrisis; en el mercado de Brasil, el efecto está presente en el sector bancario en el periodo total y en el subperiodo de precrisis; en el mercado de Argentina tal efecto se presentó en el sector bancario y en el sector de petróleo y gas, y en el mercado de México no existe ninguna evidencia de dicho efecto.

https://doi.org/10.1016/j.cya.2015.12.002 1356 downloads

Estimación de propiedades mecánicas de roca utilizando inteligencia artificial
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Galvis Carreño, Laura Viviana

; Ochoa, Cesar Augusto

; Arguello Fuentes, Henry

; Carvajal Jiménez, Jenny Mabel

; Calderón Carrillo, Zuly Himelda

Ingeniería y Ciencia

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Dez 2011, Volume 7 Nº 14 Páginas 83 - 103

Resumo: Es En Pt | Texto: Es En Pt | PDF: Es | PDF: En | PDF: Pt

Este artículo presenta la forma como fueron combinadas dos técnicas de inteligencia artificial, redes neuronales y algoritmos genéticos, para el desarrollo de una herramienta computacional utilizada para la estimación de propiedades mecánicas tales como la resistencia a la tensión, la resistencia a la compresión uniaxial y la resistencia a la compresión triaxial en areniscas, a partir de propiedades petrofísicas utilizando datos de pruebas del Laboratorio de Mecánica de Rocas del Instituto Colombiano del Petróleo - Ecopetrol S.A. como datos de entrenamiento facilitando el diseño de ensayos no destructivos con cierto grado de confianza y dando lugar a una reducción de costos.

This paper discusses how two artificial intelligence techniques were combined, neural networks and genetic algorithms for the development of a computational tool used for the estimation of mechanical properties such as tensile strength, uniaxial compressive strength and triaxial compressive strength in sandstones, from petrophysical properties using data from tests of Rock Mechanics Laboratory of the Colombian Petroleum Institute Ecopetrol SA as training data, to improve the design of non-destructive testing with some degree of confidence and resulting in cost reduction.

Este artigo discute como duas técnicas foram combinadas de inteligência artificial, redes neurais e algoritmos genéticos para o desenvolvimento de uma ferramenta computacional utilizada para o cálculo das propriedades mecânicas como resistência à tração, resistência à compressão uniaxial e resistência à compressão triaxial em arenitos de propriedades petrofísicas utilizando dados de testes do Laboratório de Mecânica das Rochas da Colômbia Petroleum Institute Ecopetrol SA como dados de treinamento para facilitar o desenho de ensaios não-destrutivos com algum grau de confiança, resultando em redução de custos.

12756 downloads

10.

Tumores gastrointestinales estromales (GIST): Experiencia del Servicio de Cirugía del Hospital Clínico de la Universidad de Chile entre 1999 y 2005
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Braghetto, Italo

; Parada, Francisco J

; Cardemil, Gonzalo

; Csendes, Attila

; Fernández, Eduardo

; Korn, Owen

; Ramírez, Marcos

; Carreño, Laura

; Smok, Gladys

; Molina, Juan Carlos

; Lembach, Hanns

Revista médica de Chile

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Mai 2007, Volume 135 Nº 5 Páginas 551 - 557

Resumo: En Es | Texto: En Es | PDF: En | PDF: Es

Background: Gastrointestinal stromal tumors (GIST) are the most common mesenchymatous tumors of the digestive tract. The pathological diagnosis is based on microscopy and immunohistochemistiy. Aim: To review the experience of our surgical unit in patients with GIST Material and methods: Review of medical records of 15 patients (aged 66+13 years, 11 women), with a pathological diagnosis of GIST, treated between 1999 and 2005. Results: The main presenting symptoms were melena in 40%, hematemesis in 20%, abdominal pain in 60% and anemia in 13%. In only one patient, the tumor appeared as an incidentaloma. All patients underwent upper gastrointestinal endoscopy A CAT scan was done in 87%, a barium swallow in 60% and a digestive endosonography in 20%. Thirteen tumors were located in the stomach and two in the small bowel. Mean tumor diameter was 5.3+1.7 cm. Surgical management was a tumor resection in 40%, a partial gastrectomy in 27%, a total gastrectomy in 20% and an intestinal excision in the rest. Mean hospital stay was 6.9+4.2 days. No postoperative complications were recorded. Conclusions: The main clinical presentation of GIST in this retrospective series was an upper gastrointestinal bleeding. Surgical treatment was devoid of complications

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11.

Fascioliasis hepática que simularon tumores hepáticos
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Sapunar, Jorge

; Braghetto, Italo

; Díaz, Juan Carlos

; Brahm, Javier

; Apt, Werner

; Carreño, Laura

; Poniachick, Jaime

Boletín chileno de parasitología

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Jul 2001, Volume 56 Nº 3-4 Páginas 59 - 65

Resumo: En Es | Texto: En Es | PDF: En | PDF: Es

Two cases of hepatic fascioliasis which simulated hepatic tumors are presented: Patient 1. (42-year-old woman), presented pain in the epigastric and right hypochondrium. US, CAT and MNR suggested a cholangiocarcinoma. She was operated on by practicing hepatic segmentectomy, cholecystectomy and closign of a cholecystogastric fistula. The extirpated hepatic segment presented a tumoral aspect, but its histopathological study revealed numerous granulomas, some of them with F. hepatica eggs and others with Charcot - Leyden crystals. ELISA and complement fixation reaction for fascioliasis resulted positive. Search of F. hepatica eggs in stools was negative. The patient was treated with triclabendazole. Patient 2. (58-year-old woman) also presented pains in the upper hemiabdomen. Hypereosinophilia (32%). Abdominal CAT showed multiple hipondense irregular zones suggesting infiltrative processes in the liver right lobe. The hepatic biopsy, under CAT, eventhough lead to think in a hamartoma, a diagnosis of chronic cholangitis compatible with a parasitic etiology raised. ELISA and complement fixation reaction for fascioliasis were positive. Coproparasitological exams for F. Hapatica resulted negative. She was successfully treated with triclabendazole. Hapatic fascioliasis simulates numerous diseases, among them hepatic tumors.

8943 downloads Citado 2 vezes em SciELO

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Você pode enriquecer sua busca de uma forma muito simples. Use os índices de pesquisa combinados com os conectores (AND ou OR) e especifique cada vez mais sua busca.

Por exemplo, se você deseja buscar artigos sobre
casos de dengue no Brasil em 2015, use:
ti:dengue and publication_year:2015 and aff_country:Brasil

Veja abaixo a lista completa de índices de pesquisa que podem ser usados:

Cód. do Índice	Elemento
ti	título do artigo
au	autor
kw	palavras-chave do artigo
subject	assunto (palavras do título, resumo e palavras-chave)
ab	resumo
ta	título abreviado da revista (ex. Cad. Saúde Pública)
journal_title	título completo da revista (ex. Cadernos de Saúde Pública)
la	código do idioma da publicação (ex. pt - Português, es - Espanhol)
type	tipo do documento
pid	identificador da publicação
publication_year	ano de publicação do artigo
sponsor	financiador
aff_country	código do país de afiliação do autor
aff_institution	instituição de afiliação do autor
volume	volume do artigo
issue	número do artigo
elocation	elocation
doi	número DOI
issn	ISSN da revista
in	código da coleção SciELO (ex. scl - Brasil, col - Colômbia)
use_license	código da licença de uso do artigo

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Email: scielo@scielo.org

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